Neurocritical care is an important and integral part of neurosurgical management. In this global war without any smoke, it is a pivotal need for a holistic effort, as a health unit, in combating the virus. In this new era of SARS-CoV-2, neurosurgeons must acknowledge the insights regarding neurocritical care to safeguard our patients and quest for their best possible clinical outcome, working in harmony and sync with other clinical specialties. SARS-CoV-2 has very similar properties to the already known SARS-CoV, demonstrating in animal models its ability to invade neural tissues, with a high preponderance to neurons in the respiratory centers. The exact cause must be differentiated from nonspecific causes from those caused valid or indirect way by the infection, including infectious, para-infectious, and post-infectious encephalitis, hyper-coagulable states prompting stroke. To improve the quality of life of patients, roping in of the neurological manpower is mandatory in ICU, ward, research as well as neurological, neuropsychological, and neurocognitive rehabilitation including domiciliary care in search of a SARS-CoV-2 free world.
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