Panamerican Journal of Trauma, Critical Care & Emergency Surgery

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VOLUME 11 , ISSUE 1 ( January-April, 2022 ) > List of Articles


Prophylactic Infusion of 3% Saline in Intracranial Hypertension: Look before you Leap

Alfonso I Pacheco-Hernandez

Keywords : Neurocritical care, Neurointensive care, Traumatic brain injury

Citation Information : Pacheco-Hernandez AI. Prophylactic Infusion of 3% Saline in Intracranial Hypertension: Look before you Leap. Panam J Trauma Crit Care Emerg Surg 2022; 11 (1):66-67.

DOI: 10.5005/jp-journals-10030-1378

License: CC BY-NC 4.0

Published Online: 24-05-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Intracranial hypertension can be a direct cause of mortality in neurointensive care. One of the strategies that have proven effective is the use of hyperosmolar fluid therapy to reduce intracranial pressure. The preference for hypertonic saline solution over mannitol has been due to the potential complications of the mannitol. These complications include renal injury and rebound intracranial hypertension. This use of hypertonic saline is sometimes used as a prophylactic administration in anticipation of cerebral insult. Administration of hypertonic saline can be bolus or continuous infusion. There are certain issues that need to be mentioned in the planning of the care. Here, we would like to visit the need for this prophylactic infusion or protocol for hypertonic saline.

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