Panamerican Journal of Trauma, Critical Care & Emergency Surgery

Register      Login

VOLUME 2 , ISSUE 2 ( May-August, 2013 ) > List of Articles

RESEARCH ARTICLE

Impact of Low Fibrinogen Levels in the Puzzle of Traumainduced Coagulopathy: Is This the Missing Link?

Peter Meade, Juan C Duchesne, Timothy S Park, Eric Simms, Jordan RH Hoffman, Jiselle M Bock, Julie Wascom, James Barbeau, Norman E McSwain Jr

Citation Information : Meade P, Duchesne JC, Park TS, Simms E, Hoffman JR, Bock JM, Wascom J, Barbeau J, Jr NE. Impact of Low Fibrinogen Levels in the Puzzle of Traumainduced Coagulopathy: Is This the Missing Link?. Panam J Trauma Crit Care Emerg Surg 2013; 2 (2):74-79.

DOI: 10.5005/jp-journals-10030-1063

License: CC BY-NC 4.0

Published Online: 01-08-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract


PDF Share
  1. Coagulopathy: its pathophysiology and treatment in the injured patient. World J Surg 2007;31(5):1055-1064.
  2. Damage control resuscitation: the new face of damage control. J Trauma 2010;69(4):976-990.
  3. Early coagulopathy predicts mortality in trauma. J Trauma 2003;55(1):39-44.
  4. Acute traumatic coagulopathy. J Trauma 2003;54(6):1127-1130.
  5. Acute coagulopathy of trauma: mechanism, identification and effect. Curr Opin Crit Care 2007 Dec;13(6):680-685.
  6. Role of fibrinogen in trauma-induced coagulopathy. Br J Anaesth 2010;105(2):116-121.
  7. Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma 2007;62(2):307-310.
  8. Damage control resuscitation for patients with major trauma. BMJ 2009;338:b1778.
  9. Hemostatic resuscitation during surgery improves survival in patients with traumaticinduced coagulopathy. J Trauma 2008;67(1):33-39.
  10. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010;376(9734):23-32.
  11. Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway. J Trauma 2007;63(6):1254-1261; discussion 1261- 1262.
  12. Damage control resuscitation: addressing trauma-induced coagulopathy. Br J Hosp Med (Lond) 2009;70(1):22-25.
  13. Frequency, risk stratification and therapeutic management of acute post-traumatic coagulopathy. Vox Sang 2009;97(1):39-49.
  14. Coagulopathy in severe traumatic brain injury: a prospective study. J Trauma 2009;66(1):55-61; discussion 61-62.
  15. The injury severity score: an update. J Trauma 1976;16(11):882-885.
  16. Hyperfibrinolysis after major trauma: differential diagnosis of lysis patterns and prognostic value of thrombo-elastometry. J Trauma 2009;67(1):125-131.
  17. Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of trauma. An Surg 2010;252:434-444.
  18. Fibrinolysis, inflammation, and regulation of the plasminogen activating system. J Thromb Haemost 2007;5(Suppl 1):132-142.
  19. Effects of hemorrhage and lactated Ringer's resuscitation on coagulation and fibrinogen metabolism in swine. Shock 2006;26(4):396-401.
  20. Hemostatic changes after crystalloid or colloid fluid administration during major orthopedic surgery: the role of fibrinogen administration. Anesth. Analg 2007;105(4):905-917.
  21. Acidosis and coagulopathy: the differential effects on fibrinogen synthesis and breakdown in pigs. Ann Surg 2007;246(5):831-835.
  22. Independent contributions of hypothermia and acidosis to coagulopathy in swine. J Trauma 2005;58(5):1002-1009; discussion 1009-1010.
  23. Multidisciplinary approach to the challenge of hemostasis. Anesth Analg 2010;110:354-364.
  24. Relative rates of tumor, normal gut, liver and fibrinogen protein synthesis in man. Am J Physiol - Endocrinol and Metabolism 1978;234(6):E648-E652.
  25. Albumin and fibrinogen synthesis and insulin effect in type 2 diabetic patients with normoal buminuria. Diabetes Care 2006;29(2):323-328.
  26. Increased albumin and fibrinogen synthesis rate in patients with chronic renal failure. Kidney Int 2003;64(4):1495-1504.
  27. Military Application of Tranexamic acid in Trauma Emergency Resuscitation (MATTERs) Study. Arch Srug 2012 Feb; 147(2): 113-119.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.