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VOLUME 12 , ISSUE 3 ( September-December, 2023 ) > List of Articles


Massive Whole Blood Transfusion Protocol: Initial Experience at Hospital de Clínicas, “Dr. Manuel Quintela,” Montevideo, Uruguay

Gabriela Rivas, Carolina S Guarneri, Marcelo Pontillo, Agustin Colombo, Jimena Bentos, Ricardo Robaina, Federico Kuster, Ismael Rodriguez, Fernando Machado

Keywords : Blood components, Hypovolemic shock, Massive transfusion, Severe trauma

Citation Information : Rivas G, Guarneri CS, Pontillo M, Colombo A, Bentos J, Robaina R, Kuster F, Rodriguez I, Machado F. Massive Whole Blood Transfusion Protocol: Initial Experience at Hospital de Clínicas, “Dr. Manuel Quintela,” Montevideo, Uruguay. Panam J Trauma Crit Care Emerg Surg 2023; 12 (3):102-109.

DOI: 10.5005/jp-journals-10030-1427

License: CC BY-NC 4.0

Published Online: 30-12-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Introduction: Massive hemorrhage (MH) is the second determinant of initial mortality in trauma patients. Its treatment requires aggressive resuscitation with blood or its components. New therapeutic schemes have been postulated, within which massive transfusion (MT) stands out. To analyze the initial experience with the application of the TM protocol in adult trauma patients admitted to the Emergency Department of the Hospital de Clínicas “Dr Manuel Quintela.” Materials and methods: A retrospective, observational, and descriptive study was carried out at the Hospital de Clínicas in the period from 1st February 2018 to 2020. Inclusion and exclusion criteria were established. Results: If we only include patients who suffered some type of trauma, the percentage of correct activation rose to 81.6% of the cases. When evaluating the mortality associated with the use of the protocol, it was shown to be significantly lower than in those in which the protocol was used without a clear indication, with a calculated p-value of 0.009. This reflects that there is an association between the need for MT and death. An association was demonstrated between the value of the Assessment of Blood Consumption (ABC) score and death (p = 0.013). Conclusion: Decreases morbidity and mortality in patients who are candidates for MT. Organizes the work group, assigning roles and establishing therapies. Appropriate the rational use of blood components, a finite and scarce good in the world such as blood donation.

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